Daphne, Roy and Jen have all slept with the same man, Carlo, unsafely. Carlo had been dating Jen, and Roy and Daphne's affairs with him had been secret. When they learn Carlo is HIV-positive, secrets find their way into the light. Daphne and Roy both start relationships with new men. Craig, whom Roy had introduced to Daphne, seems to be a solid, dependable guy. But, after a few dates, Craig learns that Daphne might be positive, and he cannot handle it. Jen meets Adam and thinks he's perfect for Roy. Their first date is right after Roy has learned that he is HIV-positive, but Adam is willing to try a relationship. Jen learns she is negative; Daphne, that she's positive. Everyone tries to pick up the pieces of their lives. Adam seems unaffected by Roy being positive. Craig tries to win Daphne back into his life and fails. Daphne, trying to repair her relationship with the media-hungry Jen, goes on a talk show, but due to Jen's machinations, the appearance backfires. Jen and Daphne stop speaking. Adam reveals that he is drawn to the idea of being the one to take care of Roy when he becomes ill. Jen, racked by self-loathing, seeks to cauterize her emotions through a self-destructive act. Craig tries one last time to convince Daphne that he can be there for her. Plagued by self-doubt, she succumbs to him. Craig sees the extent of Daphne's uncertainty and need and pulls away from her even as she clings to him.