Danny Zuko – The leader of the Burger Palace Boys; good-looking, strong and confident, with an air of easy-going charm
Sandy Dumbrowski – New girl in town; sweet, wholesome, naive, cute, and innocent
Betty Rizzo – Leader of the Pink Ladies; tough, sarcastic and outspoken but vulnerable
Frenchy – a dreamer; good-natured but not too smart, she is heavily made up, fussy about her appearance, particularly her hair. She can't wait to finish high school so she can be a beautician
Marty – the 'beauty' of the Pink Ladies; pretty and looks older than the other girls, but betrays her real age when she opens her mouth. She tries to act sophisticated.
Jan – Funny, loud, compulsive eater and awkward member of the Pink Ladies. Loud and pushy with the girls, but shy with boys
Doody – the youngest of the guys; small, boyish and open, with a disarming smile and a hero-worshipping attitude towards the other guys. He also plays the guitar.
Kenickie – the second in command of the Burger Palace Boys; tough-looking, tattooed, surly and avoids any show of softness. He has an offbeat sense of humor.
Sonny LaTierri – a member of the Burger Palace Boys; funny Italian-American, he is a braggart and wheeler-dealer who thinks he's a real lady-killer
Roger – the anything-for-a-laugh stocky type of boy; a clown who enjoys winding people up, he is full of mischief and is always dreaming up half-baked schemes and ideas
Vince Fontaine – a typical 'teen audience' disc jockey; slick, egotistical and fast-talking. He is also a veteran 'Greaser.'
Cha-Cha, aka Charlene DiGregorio - the best dancer at St. Bernadette's; a loud mouth, she wins the dancing competition with Danny.
Eugene Florczyk – the class valedictorian; physically awkward, with weak eyes and a high-pitched voice. He's a typical 'apple-polisher' - both smug and pompous, but gullible.
Johnny Casino – All-American, rock-star “greaser” student at Rydell High, whose real name is Clarence
Miss Lynch – A no-nonsense, serious, loud, English teacher
Patty Simcox – a typical cheerleader; attractive, athletic, sure-of-herself, but can be given to bursts of disconcerting enthusiasm. She's a bit of a pain and unpopular with the Pink Ladies, and can twirl a baton.
The Pink Ladies - the club-jacketed, gum-chewing, hip-swinging girls' gang who hang around with the Burger Palace Boys.
The Burger Palace Boys - A super-cool, DA-haired, hard-looking group of high school wheeler-dealers... or so they think.